Recent Publications
Selected Publications
(2011) The RPT2 subunit of the 26S proteasome directs complex assembly, histone dynamics, and gametophyte and sporophyte development in Arabidopsis. Plant Cell. 12:4298-317.
(2011) The ATG1/ATG13 protein kinase complex is both a regulator and a target of autophagic recycling in Arabidopsis. Plant Cell. 10:3761-79.
(2011) Phylogenetic comparison of F-Box (FBX) gene superfamily within the plant kingdom reveals divergent evolutionary histories indicative of genomic drift. PLoS ONE. 6(1): e16219.
(2010) Proteomic analyses identify a diverse array of nuclear processes affected by small ubiquitin-like modifier conjugation in Arabidopsis. Proc Natl Acad Sci U S A. 38:16512-7.
(2010) Quaternary organization of a phytochrome dimer as revealed by cryoelectron microscopy. Proc Natl Acad Sci U S A. 24:10872-7.
(2010) Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. J. Biol. Chem. 33:25554-69.
(2010) ATG8 lipidation and ATG8-mediated autophagy in Arabidopsis require ATG12 expressed from the differentially controlled ATG12A AND ATG12B loci. Plant J. 3:483-93.
(2010) The RAD23 Family Provides an Essential Connection between the 26S Proteasome and Ubiquitylated Proteins in Arabidopsis. Plant Cell 1:124-42.
(2010) Stuctural basis for the photoconversion of a phytochrome to the activated Pfr form. Nature 463:250-254
(2009) Cyanochromes:blue-green light photoreversible phytochromes defined by a stable double cysteine linkage to a phycoviolobilin-type chromophore. J. Biol. Chem. 284: 29757-72
(2009) The ubiquitin/26S proteasome system at the nexus of plant development. Nat. Rev. Mol. Cell Biol. 10: 385-397.
(2009) Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Plant J. 59: 344-358.
(2009) The RPN5 subunit of the 26S proteasome is essential for gametogenesis, sporophyte development, and complex assembly in Arabidopsis. Plant Cell 21: 460-478.
(2009) The BTB ubiquitin ligases ETO1, EOL1 and EOL2 act collectively to regulate ethylene biosynthesis in Arabidopsis by controlling type-2 ACC synthase levels.Plant J. 57: 332-345.
(2009) The ATG autophagic conjugation system in maize: Atg transcripts and abundance of the ATG8-lipid adduct are regulated by development and nutrient availability. Plant Physiol. 149: 220-234.
(2008) The solution structure of a cyanobacterial phytochrome GAF domain in the red light-absorbing ground state. J. Mol. Biol. 383: 403-413.
(2008) Characterization of two thermostable cyanobacterial phytochromes reveals global movements in the chromophore binding domain during photoconversion. J. Biol. Chem. 283: 21251-21266.
(2008) The ATG12-conjugating enzyme ATG10 is essential for autophagic vesicle formation in Arabidopsis thaliana. Genetics. 178: 1339-1353.
(2008) Mutational analysis of Deinococcus radiodurans bacteriophytochrome reveals key amino acids necessary for the photochromicity and proton exchange cycle of phytochromes. J. Biol. Chem. 283: 12212-12226.
(2007) Large-scale, lineage-specific expansion of the Bric-a Brac/Tramtrack/Broad Complex (BTB) ubiquitin-ligase gene family in rice. Plant Cell. 19: 2329-2348.
(2007) The ubiquitin-specific protease subfamily UBP3/UBP4 is essential for pollen development and transmission in Arabidopsis thaliana. Plant Physiol. 145: 801-183.
(2007) Genetic analysis of the SUMOylation in Arabidopsis: conjugation of SUMO1 and 2 to nuclear proteins is essential. Plant. Physiol. 145: 119-134.
(2007) Attenuation of brassinosteriod signaling enhances FLC expression and delays flowering. Development 134: 2841-2850. (paper featured on front cover)
(2007) Ubiquitin carboxy-terminal hydrolase 1 and 2 affect shoot architecture in Arabidopsis. Plant J. 51: 441-457.
(2007) High resolution structure of Deinococcus bacteriophytochrome yields new insights in phytochrome architecture and evolution. J. Biol. Chem. 282: 12298-12309.
(2007) Ubiquitin-based vectors for the stoichiometric production of multiple proteins in plants. Plant Biotech. J. 5: 413-421
(2007) The Arabidopsis EIN3-binding F-box proteins, EBF1 and EBF2 have distinct but overlapping roles in the control of ethylene signaling. Plant Cell 19: 509-523.
(2006) KEEP ON GOING, a RING E3 ligase essential for Arabidopsis growth and development, is involved in abscisic acid signaling. Plant Cell. 18: 3415-3428.
(2006) The exonuclease XRN4 is a component of the ethylene response pathway in Arabidopsis. Plant Cell 18: 3047-3057.
(2006) MUBs, a family of ubiquitin-fold proteins that are plasma membrane-anchored by prenylation. J. Biol. Chem. 281: 27145-27157. (paper featured on front cover)
(2006) Multiple heme oxygenase family members contribute to the biosynthesis of the phytochrome chromophore in Arabidopsis. Plant Physiol. 140: 856-868.
(2005) Genetic and molecular analysis of phytochromes from the filamentous fungus Neurospora crassa. Eukaroytic Cell 4: 2140-2152.
(2005) Functional analysis of bacteriophytochromes In: Photomorphogenesis in Plant and Bacteria: Function and Signal Transduction Mechanisms (E. Schafer ed) Kulwer Academic Publishers, Dordrecht, The Netherlands. pgs 65-98..
(2005) A light-sensing knot revealed by the structure of the chromophore-binding domain of phytochrome. Nature 438: 325-331. (article featured by The Plant Cell)
(2005) Phylogenetic analysis of thephytochrome superfamily reveals distinct subfamilies of microbial photoreceptors. Biochem.J. 392: 103-116.
(2005) Autophagic nutrient recycling in Arabidopsis thaliana directed by the ATG8 and ATG12 conjugation pathways. Plant Physiol. 138: 2097-2110.
(2005) Tripeptidyl peptidase (TPP)-II, an oligomeric protease complex from Arabidopsis. Plant Physiol. 138: 1046-1057.
(2005) Cullin 3A and B assemble with members of the broad complex/tramtrack/bric-a-brac (BTB) protein family to form essential ubiquitin-protein ligases in Arabidopsis. J. Biol Chem. 280: 18810-18821.
(2005) Autophagic recycling: lessons from yeast help define the process in plants. Curr. Opin. Plant Biol. . 8: 165-173.
(2005) Phytochromes in microorganisms. In: Handbook of Photosensory Receptors (W.R. Briggs and J.L. Spudich, eds). Wiley-VCH Press, Wehiheim Germany. pp 171-195.
(2004) Arabidopsis EIN3-binding F-box 1 and 2 form ubiquitin-protein ligases that repress ethylene action and promote growth by directing EIN3 degradation. Proc.Natl. Acad. Sci. USA 101: 6803-6808.
(2004) Purification of the Arabidopsis 26S proteasome: biochemical and molecular analyses revealed the presence multiple isoforms. J. Biol. Chem. 279: 6401-6413.
(2004) The ubiquitin 26S proteasome proteolytic pathway. Ann. Rev. Plant Biol. 55: 555-590.
(2004) The HWE histidine kinases, a new family of bacterial two-component sensor kinases with potentially diverse roles in environmental signaling. J. Bactertiol. 186: 445-453 (paper was chosen as the feature article).
(2003) The ubiquitin/26S proteasome pathway, the complex last chapter in the life of many plant proteins. Trends Plant Sci. 8: 135-142
(2003) Plant reproduction–sex and self denial. Nature 423: 229-230.
(2003) The HECT ubiquitin-protein ligase family in Arabidopsis: UPL3 has a specific role in trichome development. Plant J. 35: 729-742.
(2003) The pleiotropic role in the 26S proteasome subunit RPN10 in Arabidopsis thaliana growth and development supports a substrate-specific function in abscisic acid signaling. Plant Cell 15: 965-980.
(2003) The pair of bacteriophytochrome from Agrobacteriumtumefaciens are histidine kinases with opposing photobiological properties. Proc. Natl. Acad. Sci. USA 100: 2807-2812.
(2003) Small ubiquitin-like modifier (SUMO) protein modification system in Arabidopsis: accumulation of SUMO conjugates is increased by stress. J. Biol. Chem. 278: 6862-6872.
(2002) The F-Box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc. Natl. Acad. Sci USA 99: 11519-11524.
(2002) The APG12/8-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana. J. Biol. Chem. 277: 33105-33114.
(2002) The cytokinin response of Arabidopsis involves the 26S proteasome subunit RPN12a. Plant Cell 14: 17-32.
(2001) Mapping subunit interactions within the regulatory particle of the 26S proteasome and the COP9-signalosome: comparisons reveal a conserved core structure. EMBO J. 24: 7096-7107.
(2001) Bacterio-phytochromes are photochromic histidine kinases using a biliverdin chromophore. Nature 414:776-779.
(2001) Mass spectrometric resolutionof reversible phosphorylation in photosynthetic membranes of Arabidopsis thaliana. J. Biol. Chem. 276: 6959-6966.
(1999) Bacteriophytochromes, phytochrome-like photoreceptors from non-photosynthetic eubacteria. Science 286: 2517-2520.
(1999) The Arabidopsis thaliana HY1 locus, required for phytochrome chromophore biosynthesis, encodes a protein related to heme oxygenases. Proc. Natl. Acad. Sci. USA. 96: 6541-6546.